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Roberto Galletto
Assistant Professor
Dept. of Biochemistry and
Molecular Biophysics |
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Mailing Address:
WUSM - Biochemistry Dept.
660 S. Euclid Ave., MS8231
St. Louis, MO 63110
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Research Interests
Mechanistic studies of DNA motor proteins.
Selected Publications
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Andreeva, I.E., Szymanski, M.R., Jezewska, M.J., Galletto, R. and Bujalowski, W. Dynamics of the ssDNA recognition by the RepA hexameric helicase of plasmid RSF 1010: Analyses using fluorescence stopped-flow intensity and anisotropy methods. J Mol Biol 388:751-775 (2009).
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Galletto, R. and Kowalczykowski, S.C. RecA. Curr Biol 17:R395-397 (2007).
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Galletto, R., Amitani, I., Baskin, R.J., Kowalczykowski, S.C. Direct observation of individual RecA filaments assembling on single DNA molecules. Nature 443:875-878 (2006).
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Galletto, R., Jezewska, M.J., Bujalowski, W. Kinetic mechanism of rat polymerase ß - dsDNA interactions. Fluorescence stopped-flow analysis of the cooperative ligand binding to a two-site one-dimensional lattice. Biochemistry 44:1251-1267 (2005).
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Galletto, R., Jezewska, M.J., Maillard, R., Bujalowski, W. The nucleotide-binding site of the Escherichia coli DnaC protein. Molecular topography of DnaC protein - nucleotide cofactor complexes. Cell Biochemistry and Biophysics 43:331-354 (2005).
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Galletto, R., Jezewska, M.J., Bujalowski, W. Kinetics of allosteric conformational transition of a macromolecule prior to ligand binding. Analysis of stopped-flow kinetic experiments. Cell Biochemistry and Biophysics 42:121-144 (2005)
