Linda Kurz Research Professor - Emeritus Dept. of Biochemistry and Molecular Biophysics

Research Interests

Macromolecular Interactions and Molecular Recognition

Selected Publications

Kurz, L.C., Constantine, C.Z., Jiang, H. and Kappock, T.J. The partial substrate dethiaacetyl-coenzyme A mimics all critical carbon acid reactions in the condensation half-reaction catalyzed by thermoplasma acidophilum citrate synthase. Biochemistry 48:7878-7891 (2009).

Kurz, L.C., Fite, B., Jean, J., Park, J., Erpelding, T. and Callis, P. Photophysics of tryptophan fluorescence: Link with the catalytic strategy of the citrate synthase from Thermoplasma acidophilum. Biochem 44:1394-1413 (2005).

Kurz, L.C., Drysdale, G., Riley, M., Tomar, M.A., Chen, J., Russell, R.J.M. and Danson, M.J. Kinetics and Mechanism of the Citrate Synthase from the Thermophilic Archaeon, Thermoplasma acidophilum, Biochemistry 39:2283-2296 (2000).

Gu, Z., Drueckhammer, D.G., Kurz, L., Liu, K., Martin, D.P., and McDermott, A. Mechanism of Condensation Reaction of Citrate Synthase as Studied by Solid State NMR: Protonation States and Hydrogen Bonding Environment in the Binding Site of Acetylcoenzyme A Analog-Citrate Synthase Complexes. Biochemistry 38:8022-8031 (1999).

Deng, H., L.C. Kurz, et al. Characterization of hydrogen bonding in the complex of adenosine deaminase with transition state analogue: a Raman spectroscopic study. Biochemistry 37:4968-4976 (1998).